Phospho-acss2
WebJul 7, 2024 · ACSS2 has been found to primarily undergo translocation from the cytoplasm to the nucleus . ACSS2 translocation is tightly connected with hormonal and transcription … WebMar 21, 2024 · ACSS2 (Acyl-CoA Synthetase Short Chain Family Member 2) is a Protein Coding gene. Diseases associated with ACSS2 include Orofacial Cleft 1 and …
Phospho-acss2
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WebJul 21, 2024 · To silence Acly and Acss2, cells were infected with 50 MOI shACLY/shACSS2 adenovectors (Vector BioLabs). To perform co-silencing of Hdac3 and Acly/Acss2, cells at the induction of differentiation ... WebNov 12, 2024 · ACSS2 is the only known enzyme that can recycle acetate derived from deacetylation reactions in the cytoplasm and nucleus of cells, including both protein and metabolite deacetylation reactions. As such, ACSS2 can recycle acetate derived from histone deacetylase reactions as well as protein deacetylation reactions mediated by …
WebSep 18, 2024 · Acetyl-CoA synthetase 2 (ACSS2) is a conserved nucleocytosolic enzyme that converts acetate to acetyl-CoA. Adult mice lacking ACSS2 appear phenotypically normal but exhibit reduced tumor burdens in mouse models of liver cancer. The normal physiological functions of this alternate pathway of acetyl-CoA synthesis remain unclear, … WebNational Center for Biotechnology Information
WebMay 25, 2024 · In the nucleus, ACSS2 binds to transcription factor EB and translocates to lysosomal and autophagy gene promoter regions, where ACSS2 incorporates acetate generated from histone acetylation turnover to locally produce acetyl-CoA for histone H3 acetylation in these regions and promote lysosomal biogenesis, autophagy, cell survival, … WebJun 11, 2024 · Abstract. Autophagy is an intracellular degenerative pathway which is responsible for neuronal survival. Under the condition of nutrient deprivation, autophagy can lead to dysfunction in memory consolidation. …
WebAnti-ACSS2 Antibody (A-9) is a mouse monoclonal IgG 1 κ ACSS2 antibody, cited in 5 publications, provided at 200 µg/ml raised against amino acids 1-160 mapping at the N-terminus of ACSS2 of human origin Anti-ACSS2 Antibody (A-9) is recommended for detection of ACSS2 of mouse, rat and human origin by WB, IP, IF and ELISA
WebDownload scientific diagram Targeting OGT or CDKs blocks GBM growth ex vivo a Representative images depicting tumor growth in organotypic brain slices derived from mice intracranially injected ... small wowWebMar 1, 2024 · VY-3-135 is a potent, stable ACSS2 inhibitor with good bioavailability. (A) Schematic of the forward reaction catalyzed by ACSS2. (B-C) Chemical structures of VY-3-249 and VY-3-135 and IC50 determinations for inhibitors against ACSS1 (blue squares) and ACSS2 (red circles). Data points represent mean (filled shapes) and replicates (empty … hilary hight woodstock ga healthgradesWebACSS2(Phospho-Ser659) Antibody Orders: [email protected] Support: [email protected] Catalog No: #58003 Package Size: #58003-1 100ul … small wr nflWebItem ACSS2 (Phospho-Ser659) Antibody; Company MyBioSource.com; Price Pricing Info Supplier Page View Company Product Page; Catalog Number MBS9459426; Clonality … small woven hanging basketWebThis gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl - … hilary hightower missouriWebImportantly, we show that ACSS2 Ser-267 phosphorylation regulates its stability by reducing polyubiquitination and degradation. ACSS2 Ser-267 is critical for OGT-mediated GBM … small wraparound deskWeb(orb1096966) ACSS2 (Phospho-Ser659) Antibody Sign in or register to save this reagent to your favourites Supplier Biorbyt Host Rabbit Type Primary Clonality Polyclonal Conjugate Unconjugated Modification Phospho (Ser659) View Product On Supplier's Website Request a Quote from Biorbyt Supplier provided information Validations None provided hilary hill dermatologist