WebJun 1, 2024 · The multidomain CCCTC-binding factor (CTCF), containing a tandem array of 11 zinc fingers (ZFs), modulates the three-dimensional organization of chromatin. We crystallized the human CTCF DNA-binding domain in … WebThe Emory Down Syndrome Project and the Study of Down Syndrome and Congenital …
A CTCF Code for 3D Genome Architecture - PMC
WebJun 26, 2009 · CTCF is a highly conserved zinc finger protein implicated in diverse regulatory functions, including transcriptional activation/repression, insulation, imprinting, and X chromosome inactivation. Here we re-evaluate data supporting these roles in the context of mechanistic insights provided by recent … WebNews and Info TTCF March 6 2024 General Assembly Minutes TTCF Mar 5, 2024 Board … phlster instructions
Is developmental synchrony enabled by CTCF residence time?
WebThe DNA is arranged in a specific manner in the 3D space of the nucleus. This arrangement is partly a consequence of the transcriptional state of the chromatin. In addition, the CTCF protein and the cohesin complex for … WebMolecular Cell Short Article Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA HideharuHashimoto,1,4 DongxueWang,1,4 JohnR.Horton,1,2 XingZhang,1,2 VictorG.Corces,3 andXiaodongCheng1,2,5,* 1Department of Biochemistry, Emory University School of Medicine, 1510 Clifton Road NE, Atlanta, GA 30322, USA … WebAnalysis of chromatin accessibility in sperm of the F1–F6 generations reveals alterations at sites containing binding motifs for CCCTC-binding factor (CTCF) at two cis-regulatory elements (CREs) of the Fto gene that correlate with transmission of obesity. phlster military discount